Needles
Twenty five year old Greek lady.

Neurobiology graduate with big dreams and no time.

Lover of all things anatomy.

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Anonymous : Why didn't you become a doctor?

The answer, for me, is very simple. I have no interest in helping and treating patients.

I am intrigued by the fundamental questions of life, the processes that generate, shape, and reshape the nervous system of the invertebrates and vertebrates, from the earliest stages of embryogenesis to the final years of life. My love lies in understanding the underlying mechanisms, and not diagnosing and suggesting treatment.

bpod-mrc:

20 May 2013

Sweet Discovery

Estimated to affect over 170 million people worldwide, diabetes is a major modern-day health concern. Caused by failure to regulate blood sugar, this disease arises because of defects in the production of insulin, a hormone that acts to decrease the levels of glucose in the blood, or in the way other tissues respond to it. Researchers have recently identified a hormone, named betatrophin, which is secreted by liver and fat tissue, and stimulates duplication of insulin-producing cells in the pancreas. Raising the levels of betatrophin makes the pancreatic cells replicate faster, and having more of these cells means that more insulin is made. In the mouse pancreas pictured, the pink spots identify a protein characteristic of replication, thus revealing that some of the cells that produce insulin (stained green) are duplicating. Also found in humans, betatrophin could provide potential alternatives to insulin injections in the treatment of diabetes.

Written by Emmanuelle Briolat

—

Published in Cell 2013
bpod-mrc: 20 May 2013 Sweet Discovery Estimated to affect over 170 million people worldwide, diabetes is a major modern-day health concern. Caused by failure to regulate blood sugar, this disease arises because of defects in the production of insulin, a hormone that acts to decrease the levels of glucose in the blood, or in the way other tissues respond to it. Researchers have recently identified a hormone, named betatrophin, which is secreted by liver and fat tissue, and stimulates duplication of insulin-producing cells in the pancreas. Raising the levels of betatrophin makes the pancreatic cells replicate faster, and having more of these cells means that more insulin is made. In the mouse pancreas pictured, the pink spots identify a protein characteristic of replication, thus revealing that some of the cells that produce insulin (stained green) are duplicating. Also found in humans, betatrophin could provide potential alternatives to insulin injections in the treatment of diabetes. Written by Emmanuelle Briolat — Douglas Melton Harvard University, USA Copyright Elsevier 2013 Published in Cell 2013

jtotheizzoe:

Wee Yeasty Beasties

Fungi are like Rodney Dangerfields of the microbial world. Funny looking, often oddly round, and they get no respect.

I mean, their name suggests that they’d be rather enjoyable to hang out with*. A new survey of the human skin ecosystem has identified some of their diverse influence on human health and biology.

For as much attention as our microbiome gets these days (need a microbiome introduction? I made a video about it), the bacteria receive most of the publicity. But as the photo above shows, many regions of our bodies are teeming with yeast and other fungi (the blue dots are yeast on a human hair). Understanding their diversity is essential to figuring out who’s a good fungi and who’s a yeast beast.

Not only is it important to understand how these various species lead to medical annoyances like toenail infections, athlete’s foot, dandruff, diaper rash, and, of course, yeast infections, but also how they interact with or are held in check by our bacterial copilots. With as many as 60 to 80 different species living on your feet, who’s welcome and who’s a ticking time bomb for a locker-room itch-fest?

Read more at NPR or check out the original research in Nature.

*That’s a “fun guy” joke. I hope you got it. Not the fungus. The joke.

jtotheizzoe: Wee Yeasty Beasties Fungi are like Rodney Dangerfields of the microbial world. Funny looking, often oddly round, and they get no respect. I mean, their name suggests that they’d be rather enjoyable to hang out with*. A new survey of the human skin ecosystem has identified some of their diverse influence on human health and biology. For as much attention as our microbiome gets these days (need a microbiome introduction? I made a video about it), the bacteria receive most of the publicity. But as the photo above shows, many regions of our bodies are teeming with yeast and other fungi (the blue dots are yeast on a human hair). Understanding their diversity is essential to figuring out who’s a good fungi and who’s a yeast beast. Not only is it important to understand how these various species lead to medical annoyances like toenail infections, athlete’s foot, dandruff, diaper rash, and, of course, yeast infections, but also how they interact with or are held in check by our bacterial copilots. With as many as 60 to 80 different species living on your feet, who’s welcome and who’s a ticking time bomb for a locker-room itch-fest? Read more at NPR or check out the original research in Nature. *That’s a “fun guy” joke. I hope you got it. Not the fungus. The joke.

medicalschool:

The human brain in cross section

medicalschool: The human brain in cross section

afracturedreality:

FluoCells® Prepared Slide #6

In response to requests from educators and instrument manufacturers, Molecular Probes offers FluoCells® prepared microscope slides, which contain multilabeled cell preparations for observation by epifluorescence or confocal microscopy.

Their “Slide #6” product contains muntjac skin fibroblasts that have been fluorescently stained. Actin filaments were labeled with phalloidin conjugated to Alexa Fluor® 488 (green). Mitochondria were tagged with anti-OxPhos Complex V inhibitor protein antibodies and visualized using goat anti-mouse IgG antibodies conjugated to Alexa Fluor® 555 (orange). Nuclei were stained with TO-PRO®-3 iodide (pseudo-colored magenta).

Photo courtesy of the Life Technologies Corporation.

afracturedreality: FluoCells® Prepared Slide #6 In response to requests from educators and instrument manufacturers, Molecular Probes offers FluoCells® prepared microscope slides, which contain multilabeled cell preparations for observation by epifluorescence or confocal microscopy. Their “Slide #6” product contains muntjac skin fibroblasts that have been fluorescently stained. Actin filaments were labeled with phalloidin conjugated to Alexa Fluor® 488 (green). Mitochondria were tagged with anti-OxPhos Complex V inhibitor protein antibodies and visualized using goat anti-mouse IgG antibodies conjugated to Alexa Fluor® 555 (orange). Nuclei were stained with TO-PRO®-3 iodide (pseudo-colored magenta). Photo courtesy of the Life Technologies Corporation.

(Source: sprezzatura-di-castiglione)

porn.

(Source: extrarouge)

porn.

scienceyoucanlove:

Fruit Fly Heart
Drosophila pumps blood through its body with a long, tube-shaped muscle.
Jianbo Na and Ross Cagan, Mount Sinai School of Medicine, PLOS Genetics, doi:10.1371/journal.pgen.1003175
http://bit.ly/Z7OXHO

source 

scienceyoucanlove: Fruit Fly HeartDrosophila pumps blood through its body with a long, tube-shaped muscle.Jianbo Na and Ross Cagan, Mount Sinai School of Medicine, PLOS Genetics, doi:10.1371/journal.pgen.1003175http://bit.ly/Z7OXHO source 

(Source: starwarsfangirl1975)

alittletreasuryoftentacles:

Octopus by quinet on Flickr.

alittletreasuryoftentacles: Octopus by quinet on Flickr.

(Source: killingstatic)

(Source: ipleasureyouwithpain)

One bag of donuts, 10 chocolate chip cookies, one big sized pizza and half a season of Sex and the City later; it’s time for bed.